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Symbol
Name
ID

Tgfbr1
transforming growth factor, beta receptor I
MGI:98728

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Gastrointestinal hemorrhage	Hematological neoplasm
Disease(s) Associated with TGFBR1	Gastrointestinal hemorrhage	Hematological neoplasm
Lynch syndrome

Mouse Phenotypes		hematopoietic system phenotype	increased hematopoietic stem cell proliferation	decreased dendritic cell number	abnormal T cell activation
Availability	Mouse Genotype	hematopoietic system phenotype	increased hematopoietic stem cell proliferation	decreased dendritic cell number	abnormal T cell activation
	Hprt1^{tm1(CAG-Tgfbr1)Lba}/Hprt1^{tm1(CAG-Tgfbr1)Lba} Tg(Cd4-cre)1Cwi/0 (conditional)
	Tgfbr1^tm1.1Karl/Tgfbr1^tm1.1Karl Tg(Mx1-cre)1Cgn/0 (conditional)	*
	Cd207^{tm2.1(cre)Bjec}/Cd207⁺ Tgfbr1^tm1.1Karl/Tgfbr1^tm1.1Karl (conditional)
	Hprt1^{tm1(CAG-Tgfbr1*)Lba}/Y Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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